UI styling update
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@ -10,11 +10,19 @@ const HiCMappingIntroduction = () => {
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"The sequenced reads are processed using advanced bioinformatics tools, starting with alignment to a reference genome, followed by the identification of chromatin loops and the construction of 3D models of genome organization.",
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"Plays pivotal role in multiple applications, including identifying promoter-enhancer interactions for gene regulation studies, detecting structural rearrangements, scaffolding contigs to define chromosomes de novo, and revealing structural errors while accurately reintegrating mis-joined contigs during genome assembly processes."
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];
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const advantageItems = [
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"Quantifies interactions between closely located genomic loci in 3-D space, despite being separated by many nucleotides in the linear genome.",
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"Provides a detailed view of the 3D architecture of the genome, helping researchers understand how chromatin folding impacts gene regulation, genome organization, and cellular function.",
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"Captures interactions between distant regions of DNA, enabling the mapping of chromatin loops, topologically associated domains (TADs), and other structural features at high resolution.",
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"By revealing interactions between regulatory elements, such as enhancers and promoters, Hi-C mapping sheds light on how gene expression is controlled at the epigenetic and transcriptional levels."
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];
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return (
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<IntroductionLayout
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title="Introduction and Workflow"
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contentItems={contentItems}
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introTitle="Introduction and Workflow"
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advantageTitle="Advantage"
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introItems={contentItems}
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advantageItems={advantageItems}
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imageUrl="/images/dna/hic-sequencing.png"
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imageAlt="Hi-C Mapping Workflow"
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useParagraphs={true}
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