UI styling update
This commit is contained in:
mukesh13
@ -8,11 +8,19 @@ const CircularIntroduction = () => {
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"The workflow starts with isolating total RNA from the sample, which includes both linear and circular RNAs. Linear RNAs are then removed through ribosomal RNA (rRNA) depletion or exonuclease treatment to enrich the circular RNA fraction. Next, the RNA is circularized, and sequencing adapters are added during library preparation. The final step involves sequencing the prepared libraries.",
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"Bioinformatics analysis for circRNA sequencing involves preprocessing data and mapping reads to a reference genome to identify back-splicing junctions. Computational tools are then used to quantify circRNA expression, discover novel circRNAs, and perform downstream analysis."
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];
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const advantageItems = [
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"Circular RNAs are inherently more stable due to their covalently closed structure, making them less susceptible to degradation and providing reliable expression data.",
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"Enables the identification of novel isoforms and splice variants that may not be detected with traditional RNA sequencing methods.",
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"Offers a detailed view of circular RNA expression and their interactions within the cell, aiding in a deeper understanding of gene regulation and cellular processes.",
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"Closed-loop structure of circRNAs minimizes potential sequencing artifacts, leading to more accurate and consistent data."
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];
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return (
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<IntroductionLayout
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title="Introduction and Workflow"
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contentItems={contentItems}
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introTitle="Introduction and Workflow"
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advantageTitle="Advantage"
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introItems={contentItems}
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advantageItems={advantageItems}
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imageUrl="/images/rna/circular_rna_sequencing.png"
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imageAlt="Circular RNA Sequencing Workflow"
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useParagraphs={true}
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@ -5,16 +5,15 @@ const CircularRNAPipeline = ({
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svgContent = null, // Pass your SVG content here as JSX
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svgUrl = "/images/flowchart/circularrna.svg",
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backgroundColor = "bg-gray-50",
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textColor = "text-gray-700",
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className = "",
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titleClassName = "",
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svgClassName = "",
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containerClassName = ""
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}) => {
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return (
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<section className={`py-6 sm:py-8 lg:py-12 ${backgroundColor} ${className}`}>
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<section className={`py-6 sm:py-8 lg:py-4 ${backgroundColor} ${className}`}>
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<div className={`container mx-auto max-w-none px-3 sm:px-4 lg:px-6 ${containerClassName}`}>
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<h2 className={`${textColor} text-left pb-4 sm:pb-6 text-xl sm:text-2xl lg:text-3xl font-normal ${titleClassName}`}>
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<h2 className={"text-3xl font-bold text-teal-700 mb-4"}>
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{title}
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</h2>
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@ -22,19 +21,19 @@ const CircularRNAPipeline = ({
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<div className="bg-white rounded-xl shadow-lg p-4 sm:p-6 lg:p-8">
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<div className="flex justify-center">
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<div className="w-full max-w-6xl">
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{/* SVG Container with responsive sizing */}
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<div className={`w-full ${svgClassName}`}>
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{/* SVG Container with responsive sizing and reduced height */}
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<div className={`w-full max-h-100 overflow-hidden ${svgClassName}`}>
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{svgUrl ? (
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// If SVG URL/path is provided
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<img
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src={svgUrl}
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alt="Flowchart diagram"
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className="w-full h-auto object-contain"
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className="w-full h-auto object-contain max-h-100"
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/>
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) : svgContent ? (
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// If SVG content is provided as JSX
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<div className="w-full">
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<div className="w-full">
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<div className="w-full max-h-100">
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<div className="w-full max-h-100 overflow-hidden">
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{svgContent}
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</div>
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</div>
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@ -8,11 +8,19 @@ const DegradomeIntroduction = () => {
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"Bioinformatics analysis for Degradome Sequencing include data preprocessing, aligning reads to reference genomes, identifying miRNA/ta-siRNA cleavage sites, and quantifying cleaved targets, revealing RNA decay dynamics and regulatory mechanisms.",
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"The method facilitates the discovery of novel miRNAs and ta-siRNAs, studies on miRNA-mediated gene regulation, and comparative RNA decay analysis across species, contributing to a comprehensive understanding of RNA life cycles."
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];
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const advantageItems = [
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"Degradome sequencing provides a focused analysis of RNA degradation, specifically targeting cleavage sites mediated by miRNAs and ta-siRNAs, making it ideal for studying gene regulation and RNA stability.",
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"By targeting degradation products, degradome sequencing minimizes the impact of intact RNAs, enhancing sensitivity for detecting miRNA targets and cleavage events.",
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"Degradome sequencing focuses on RNA cleavage sites, eliminating the need for additional steps like ribosomal RNA removal, making it a more cost-effective alternative to broader transcriptome studies.",
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"Degradome sequencing enables the identification of novel regulatory elements, such as circRNAs and biomarkers, expanding its utility in understanding RNA regulatory networks."
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];
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return (
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<IntroductionLayout
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title="Introduction and Workflow"
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contentItems={contentItems}
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introTitle="Introduction and Workflow"
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advantageTitle="Advantage"
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introItems={contentItems}
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advantageItems={advantageItems}
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imageUrl="/images/rna/degradome_sequencing.png"
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imageAlt="Degradome Sequencing Workflow"
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useParagraphs={true}
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@ -5,16 +5,15 @@ const DegradomeSequencingPipeline = ({
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svgContent = null, // Pass your SVG content here as JSX
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svgUrl = "/images/flowchart/degradomerna.svg",
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backgroundColor = "bg-gray-50",
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textColor = "text-gray-700",
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className = "",
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titleClassName = "",
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svgClassName = "",
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containerClassName = ""
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}) => {
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return (
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<section className={`py-6 sm:py-8 lg:py-12 ${backgroundColor} ${className}`}>
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<section className={`py-6 sm:py-8 lg:py-4 ${backgroundColor} ${className}`}>
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<div className={`container mx-auto max-w-none px-3 sm:px-4 lg:px-6 ${containerClassName}`}>
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<h2 className={`${textColor} text-left pb-4 sm:pb-6 text-xl sm:text-2xl lg:text-3xl font-normal ${titleClassName}`}>
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<h2 className={"text-3xl font-bold text-teal-700 mb-4"}>
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{title}
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</h2>
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@ -22,19 +21,19 @@ const DegradomeSequencingPipeline = ({
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<div className="bg-white rounded-xl shadow-lg p-4 sm:p-6 lg:p-8">
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<div className="flex justify-center">
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<div className="w-full max-w-6xl">
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{/* SVG Container with responsive sizing */}
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<div className={`w-full ${svgClassName}`}>
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{/* SVG Container with responsive sizing and reduced height */}
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<div className={`w-full max-h-100 overflow-hidden ${svgClassName}`}>
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{svgUrl ? (
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// If SVG URL/path is provided
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<img
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src={svgUrl}
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alt="Flowchart diagram"
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className="w-full h-auto object-contain"
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className="w-full h-auto object-contain max-h-100"
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/>
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) : svgContent ? (
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// If SVG content is provided as JSX
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<div className="w-full">
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<div className="w-full">
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<div className="w-full max-h-100">
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<div className="w-full max-h-100 overflow-hidden">
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{svgContent}
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</div>
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</div>
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@ -20,7 +20,6 @@ export default function DegradomeSequencingPage() {
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breadcrumbs={breadcrumbs}
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/>
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<DegradomeIntroduction />
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<DegradomeAdvantages />
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<DegradomeSequencingPipeline/>
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<DegradomeApplications />
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<DegradomeSpecifications />
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@ -9,11 +9,19 @@ const IsoIntroduction = () => {
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"The bioinformatics analysis of Iso-Seq data involves assembling full-length transcripts, annotating them, and comparing them to reference genomes or existing databases. This detailed analysis reveals the complexity of gene expression, including novel isoforms and splice variants, and aids in understanding their functional roles in various biological processes.",
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"Iso-Seq using PacBio is particularly valuable for exploring gene expression at a granular level, discovering novel transcripts, and enhancing annotations of complex genomes."
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];
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const advantageItems = [
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"Unlike traditional methods, which may miss complex isoforms or splice variants, Iso-Seq captures full-length RNA sequences, enabling the identification of all transcript isoforms, including those with complex splicing and alternative start or end sites.",
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"Provides high-fidelity data with long read lengths, reducing errors and missing information common in shorter-read sequencing methods.",
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"Reduces challenges with transcript assembly and alignment by providing full-length reads that eliminate ambiguities and enhance transcriptome reconstruction accuracy. Improves genome annotations by precisely identifying gene structures, exons, introns, and regulatory elements, leading to more accurate functional insights.",
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"Uncovers novel isoforms, splice variants, and post-transcriptional modifications, providing a comprehensive view of gene expression. This detailed approach is essential for functional genomics, transcriptomics, and alternative splicing studies, offering valuable insights into gene regulation and function."
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];
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return (
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<IntroductionLayout
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title="Introduction and Workflow"
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contentItems={contentItems}
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introTitle="Introduction and Workflow"
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advantageTitle="Advantage"
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introItems={contentItems}
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advantageItems={advantageItems}
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imageUrl="/images/rna/ISO_sequencing_using_pacBio.png"
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imageAlt="ISO Sequencing using PacBio Workflow"
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useParagraphs={true}
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@ -5,16 +5,15 @@ const IsoformPipeline = ({
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svgContent = null, // Pass your SVG content here as JSX
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svgUrl = "/images/flowchart/isoseqrna.svg",
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backgroundColor = "bg-gray-50",
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textColor = "text-gray-700",
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className = "",
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titleClassName = "",
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svgClassName = "",
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containerClassName = ""
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}) => {
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return (
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<section className={`py-6 sm:py-8 lg:py-12 ${backgroundColor} ${className}`}>
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<section className={`py-6 sm:py-8 lg:py-4 ${backgroundColor} ${className}`}>
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<div className={`container mx-auto max-w-none px-3 sm:px-4 lg:px-6 ${containerClassName}`}>
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<h2 className={`${textColor} text-left pb-4 sm:pb-6 text-xl sm:text-2xl lg:text-3xl font-normal ${titleClassName}`}>
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<h2 className={"text-3xl font-bold text-teal-700 mb-4"}>
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{title}
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</h2>
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@ -22,19 +21,19 @@ const IsoformPipeline = ({
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<div className="bg-white rounded-xl shadow-lg p-4 sm:p-6 lg:p-8">
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<div className="flex justify-center">
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<div className="w-full max-w-6xl">
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{/* SVG Container with responsive sizing */}
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<div className={`w-full ${svgClassName}`}>
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{/* SVG Container with responsive sizing and reduced height */}
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<div className={`w-full max-h-100 overflow-hidden ${svgClassName}`}>
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{svgUrl ? (
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// If SVG URL/path is provided
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<img
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src={svgUrl}
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alt="Flowchart diagram"
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className="w-full h-auto object-contain"
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className="w-full h-auto object-contain max-h-100"
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/>
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) : svgContent ? (
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// If SVG content is provided as JSX
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<div className="w-full">
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<div className="w-full">
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<div className="w-full max-h-100">
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<div className="w-full max-h-100 overflow-hidden">
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{svgContent}
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</div>
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</div>
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@ -20,7 +20,6 @@ export default function IsoSequencingPage() {
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breadcrumbs={breadcrumbs}
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/>
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<IsoIntroduction />
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<IsoAdvantages />
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<IsoformPipeline/>
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<IsoApplications />
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<IsoSpecifications />
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@ -5,16 +5,15 @@ const LncRNABioinformatics = ({
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svgContent = null, // Pass your SVG content here as JSX
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svgUrl = "/images/flowchart/totalrna.svg",
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backgroundColor = "bg-gray-50",
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textColor = "text-gray-700",
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className = "",
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titleClassName = "",
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svgClassName = "",
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containerClassName = ""
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}) => {
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return (
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<section className={`py-6 sm:py-8 lg:py-12 ${backgroundColor} ${className}`}>
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<section className={`py-6 sm:py-8 lg:py-4 ${backgroundColor} ${className}`}>
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<div className={`container mx-auto max-w-none px-3 sm:px-4 lg:px-6 ${containerClassName}`}>
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<h2 className={`${textColor} text-left pb-4 sm:pb-6 text-xl sm:text-2xl lg:text-3xl font-normal ${titleClassName}`}>
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<h2 className={"text-3xl font-bold text-teal-700 mb-4"}>
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{title}
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</h2>
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@ -22,19 +21,19 @@ const LncRNABioinformatics = ({
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<div className="bg-white rounded-xl shadow-lg p-4 sm:p-6 lg:p-8">
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<div className="flex justify-center">
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<div className="w-full max-w-6xl">
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{/* SVG Container with responsive sizing */}
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<div className={`w-full ${svgClassName}`}>
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{/* SVG Container with responsive sizing and reduced height */}
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<div className={`w-full max-h-180 overflow-hidden ${svgClassName}`}>
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{svgUrl ? (
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// If SVG URL/path is provided
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<img
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src={svgUrl}
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alt="Flowchart diagram"
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className="w-full h-auto object-contain"
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className="w-full h-auto object-contain max-h-180"
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/>
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) : svgContent ? (
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// If SVG content is provided as JSX
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<div className="w-full">
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<div className="w-full">
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<div className="w-full max-h-180">
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<div className="w-full max-h-180 overflow-hidden">
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{svgContent}
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</div>
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</div>
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@ -8,11 +8,19 @@ const LncRNAIntroduction = () => {
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"The bioinformatics pipeline for lncRNA sequencing involves the alignment of sequencing data to reference genomes, identification of lncRNAs, quantification of their expression level, and other downstream analyses.",
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"lncRNA sequencing uncovers their roles in gene regulation and highlights their various functions, including chromatin remodeling, transcriptional control, nucleosome repositioning, and post-transcriptional processing."
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];
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const advantageItems = [
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"Identifies both well-known and novel lncRNAs, providing fresh insights into their roles and potential as biomarkers.",
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"Reveals lncRNAs' involvement in a broad range of molecular functions, such as chromatin remodeling, which is essential for regulating gene expression. This process includes modifying chromatin structure to control gene accessibility and influencing various cellular mechanisms, demonstrating lncRNAs' crucial roles in gene regulation and cellular function across mammals and plants.",
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"Provides a thorough understanding of lncRNAs' roles in gene regulation, encompassing both transcriptional and post-transcriptional levels. It highlights how lncRNAs affect transcription factors, alter nucleosome positioning, and contribute to RNA splicing and stability, thus impacting overall gene expression and cellular processes.",
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"Enables high-resolution analysis, allowing for precise detection and detailed characterization of lncRNA expression and their regulatory networks, offering a deep dive into their functional roles within cells."
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];
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return (
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<IntroductionLayout
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title="Introduction and Workflow"
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contentItems={contentItems}
|
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introTitle="Introduction and Workflow"
|
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advantageTitle="Advantage"
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introItems={contentItems}
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advantageItems={advantageItems}
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imageUrl="/images/rna/lncRNA_sequencing.png"
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imageAlt="lncRNA Sequencing Workflow"
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useParagraphs={true}
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@ -21,7 +21,6 @@ export default function LncRNASequencingPage() {
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breadcrumbs={breadcrumbs}
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/>
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<LncRNAIntroduction />
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<LncRNAAdvantages />
|
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<LncRNABioinformatics />
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<LncRNAApplications />
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<LncRNASpecifications />
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@ -8,11 +8,19 @@ const MetatranscriptomicsIntroduction = () => {
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"The bioinformatics workflow includes preprocessing the raw sequencing reads, performing quality control, and normalizing the data. The reads are mapped to reference genomes or databases to quantify gene expression levels. Functional annotation and pathway analysis are then carried out to understand the roles of various transcripts and their impact on microbial community functions.",
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"Metatranscriptomics is applicable to a wide range of environmental samples, such as soil, oceans, and the human gut, facilitating studies on microbial diversity, disease mechanisms, nutrient cycling, and environmental adaptation."
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];
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const advantageItems = [
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"Provides insights into the functional dynamics of microorganisms by revealing active gene expression and their roles within complex communities. This approach uncovers how microorganisms contribute to ecosystem processes and their interactions.",
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"Analyzes microbial communities directly from environmental samples, removing the need for isolating or cultivating individual microbes. This method captures a more comprehensive view of microbial diversity.",
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"Uses next-generation sequencing (NGS) to identify novel genes and track transcriptional changes, offering high-resolution data on gene expression. This allows for precise identification of active genes, pathways, and regulatory networks within microbial communities.",
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"Offers an advantage over metagenomics by including both microbial species information and gene expression data. This dual focus provides a deeper understanding of microbial community changes from a transcriptional perspective and aids in the discovery of potential new genes."
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];
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|
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return (
|
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<IntroductionLayout
|
||||
title="Introduction and Workflow"
|
||||
contentItems={contentItems}
|
||||
introTitle="Introduction and Workflow"
|
||||
advantageTitle="Advantage"
|
||||
introItems={contentItems}
|
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advantageItems={advantageItems}
|
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imageUrl="/images/rna/Metatranscriptomics.png"
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imageAlt="Metatranscriptomics Workflow"
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useParagraphs={true}
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@ -5,16 +5,15 @@ const MetatranscriptomicsPipeline = ({
|
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svgContent = null, // Pass your SVG content here as JSX
|
||||
svgUrl = "/images/flowchart/metatranscriptomicsrna.svg",
|
||||
backgroundColor = "bg-gray-50",
|
||||
textColor = "text-gray-700",
|
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className = "",
|
||||
titleClassName = "",
|
||||
svgClassName = "",
|
||||
containerClassName = ""
|
||||
}) => {
|
||||
return (
|
||||
<section className={`py-6 sm:py-8 lg:py-12 ${backgroundColor} ${className}`}>
|
||||
<section className={`py-6 sm:py-8 lg:py-4 ${backgroundColor} ${className}`}>
|
||||
<div className={`container mx-auto max-w-none px-3 sm:px-4 lg:px-6 ${containerClassName}`}>
|
||||
<h2 className={`${textColor} text-left pb-4 sm:pb-6 text-xl sm:text-2xl lg:text-3xl font-normal ${titleClassName}`}>
|
||||
<h2 className={"text-3xl font-bold text-teal-700 mb-4"}>
|
||||
{title}
|
||||
</h2>
|
||||
|
||||
@ -22,19 +21,19 @@ const MetatranscriptomicsPipeline = ({
|
||||
<div className="bg-white rounded-xl shadow-lg p-4 sm:p-6 lg:p-8">
|
||||
<div className="flex justify-center">
|
||||
<div className="w-full max-w-6xl">
|
||||
{/* SVG Container with responsive sizing */}
|
||||
<div className={`w-full ${svgClassName}`}>
|
||||
{/* SVG Container with responsive sizing and reduced height */}
|
||||
<div className={`w-full max-h-100 overflow-hidden ${svgClassName}`}>
|
||||
{svgUrl ? (
|
||||
// If SVG URL/path is provided
|
||||
<img
|
||||
src={svgUrl}
|
||||
alt="Flowchart diagram"
|
||||
className="w-full h-auto object-contain"
|
||||
className="w-full h-auto object-contain max-h-100"
|
||||
/>
|
||||
) : svgContent ? (
|
||||
// If SVG content is provided as JSX
|
||||
<div className="w-full">
|
||||
<div className="w-full">
|
||||
<div className="w-full max-h-100">
|
||||
<div className="w-full max-h-100 overflow-hidden">
|
||||
{svgContent}
|
||||
</div>
|
||||
</div>
|
||||
|
||||
@ -20,7 +20,6 @@ export default function MetatranscriptomicsSequencingPage() {
|
||||
breadcrumbs={breadcrumbs}
|
||||
/>
|
||||
<MetatranscriptomicsIntroduction />
|
||||
<MetatranscriptomicsAdvantages />
|
||||
<MetatranscriptomicsPipeline/>
|
||||
<MetatranscriptomicsApplications />
|
||||
<MetatranscriptomicsSpecifications />
|
||||
|
||||
@ -2,17 +2,25 @@
|
||||
import IntroductionLayout from '../../../components/shared/IntroductionLayout';
|
||||
|
||||
const MRNAIntroduction = () => {
|
||||
const contentItems = [
|
||||
const introItems = [
|
||||
"Messenger RNA-Seq (mRNA-Seq) is a focused RNA-Seq method that targets polyadenylated (poly-A) transcripts, which comprise only about 1-2% of the transcriptome, mainly representing coding genes. By enriching these poly-A-tailed RNAs, mRNA-Seq offers a precise snapshot of gene expression, capturing the complete range of mRNA transcripts within a sample and enabling detailed analysis of gene activity across various conditions.",
|
||||
"mRNA-seq workflow typically includes RNA extraction, enrichment or depletion of mRNA, library preparation, and high-throughput sequencing. This workflow ensures precise and efficient capture of mRNA transcripts for thorough downstream analysis.",
|
||||
"Bioinformatics analysis for mRNA-seq involves several key steps: data preprocessing, alignment to a reference genome, quantifying gene expression levels, and advanced downstream analyses such as differential expression, pathway enrichment, and gene ontology analysis.",
|
||||
"Widely applicable across diverse research fields, including human, animal, and plant studies, providing profound insights into genetic landscapes and contributing to our understanding of gene function and regulation."
|
||||
];
|
||||
const advantageItems = [
|
||||
"mRNA-Seq provides a targeted analysis of gene expression specific to protein-coding regions, making it ideal for studies focused on gene regulation, protein synthesis, and disease-related expression changes.",
|
||||
"mRNA-Seq focuses on mRNA enrichment, which minimizes the impact of non-coding RNAs and enhances sensitivity for detecting gene expression changes.",
|
||||
"Focusing solely on coding regions, mRNA-Seq does not require rRNA-specific probes (Costly) for ribosomal RNA removal and requires comparatively lesser data, making it a more cost-effective alternative to Whole Transcriptome Sequencing.",
|
||||
"With a more targeted dataset, the bioinformatics analysis of mRNA-Seq is often simpler and faster, focusing on coding genes without the complexity introduced by non-coding RNAs."
|
||||
];
|
||||
|
||||
return (
|
||||
<IntroductionLayout
|
||||
title="Introduction and Workflow"
|
||||
contentItems={contentItems}
|
||||
introTitle="Introduction and Workflow"
|
||||
advantageTitle="Advantage"
|
||||
introItems={introItems}
|
||||
advantageItems={advantageItems}
|
||||
imageUrl="/images/rna/mRNA_sequencing.png"
|
||||
imageAlt="mRNA Sequencing Workflow"
|
||||
useParagraphs={true}
|
||||
|
||||
@ -5,16 +5,15 @@ const MRNAPipeline = ({
|
||||
svgContent = null, // Pass your SVG content here as JSX
|
||||
svgUrl = "/images/flowchart/mrna.svg",
|
||||
backgroundColor = "bg-gray-50",
|
||||
textColor = "text-gray-700",
|
||||
className = "",
|
||||
titleClassName = "",
|
||||
svgClassName = "",
|
||||
containerClassName = ""
|
||||
}) => {
|
||||
return (
|
||||
<section className={`py-6 sm:py-8 lg:py-12 ${backgroundColor} ${className}`}>
|
||||
<section className={`py-6 sm:py-8 lg:py-4 ${backgroundColor} ${className}`}>
|
||||
<div className={`container mx-auto max-w-none px-3 sm:px-4 lg:px-6 ${containerClassName}`}>
|
||||
<h2 className={`${textColor} text-left pb-4 sm:pb-6 text-xl sm:text-2xl lg:text-3xl font-normal ${titleClassName}`}>
|
||||
<h2 className={"text-3xl font-bold text-teal-700 mb-4"}>
|
||||
{title}
|
||||
</h2>
|
||||
|
||||
@ -22,19 +21,19 @@ const MRNAPipeline = ({
|
||||
<div className="bg-white rounded-xl shadow-lg p-4 sm:p-6 lg:p-8">
|
||||
<div className="flex justify-center">
|
||||
<div className="w-full max-w-6xl">
|
||||
{/* SVG Container with responsive sizing */}
|
||||
<div className={`w-full ${svgClassName}`}>
|
||||
{/* SVG Container with responsive sizing and reduced height */}
|
||||
<div className={`w-full max-h-180 overflow-hidden ${svgClassName}`}>
|
||||
{svgUrl ? (
|
||||
// If SVG URL/path is provided
|
||||
<img
|
||||
src={svgUrl}
|
||||
alt="Flowchart diagram"
|
||||
className="w-full h-auto object-contain"
|
||||
className="w-full h-auto object-contain max-h-180"
|
||||
/>
|
||||
) : svgContent ? (
|
||||
// If SVG content is provided as JSX
|
||||
<div className="w-full">
|
||||
<div className="w-full">
|
||||
<div className="w-full max-h-180">
|
||||
<div className="w-full max-h-180 overflow-hidden">
|
||||
{svgContent}
|
||||
</div>
|
||||
</div>
|
||||
|
||||
@ -21,7 +21,6 @@ export default function MRNASequencingPage() {
|
||||
breadcrumbs={breadcrumbs}
|
||||
/>
|
||||
<MRNAIntroduction />
|
||||
<MRNAAdvantages />
|
||||
<MRNAPipeline/>
|
||||
<MRNAApplications />
|
||||
<MRNASpecifications />
|
||||
|
||||
@ -8,11 +8,19 @@ const SingleCellIntroduction = () => {
|
||||
"The bioinformatics pipeline includes data preprocessing, which involves quality control and normalization of the sequencing reads. The reads are then aligned to a reference genome or transcriptome to identify gene expression levels in each cell. Subsequent analysis involves clustering of cells based on expression profiles, differential gene expression analysis, and the identification of cell types and states.",
|
||||
"Single-cell high-resolution transcriptome profiling offers valuable insights into gene regulatory networks and unveils diverse gene expression patterns within individual cells across cell cultures, tissues, and organs."
|
||||
];
|
||||
const advantageItems = [
|
||||
"Unlike traditional bulk RNA sequencing, which averages gene expression across many cells and can hide unique cellular differences, single-cell RNA sequencing examines each cell individually. This reveals variations in gene expression and provides detailed insights into cellular functions, development, and disease mechanisms that are often lost in population-level data.",
|
||||
"Enables the discovery and characterization of rare or previously unrecognized cell populations, essential for understanding complex biological systems and disease mechanisms.",
|
||||
"Delivers high-resolution data on gene expression patterns, allowing for precise mapping of gene regulatory networks and cellular states, and uncovering intricate details of cellular interactions.",
|
||||
"Supports the identification of biomarkers and therapeutic targets by offering a detailed snapshot of gene activity specific to individual cell types or states, facilitating more targeted and effective research and treatments."
|
||||
];
|
||||
|
||||
return (
|
||||
<IntroductionLayout
|
||||
title="Introduction and Workflow"
|
||||
contentItems={contentItems}
|
||||
introTitle="Introduction and Workflow"
|
||||
advantageTitle="Advantage"
|
||||
introItems={contentItems}
|
||||
advantageItems={advantageItems}
|
||||
imageUrl="/images/rna/Single_cell_RNA_sequencing.png"
|
||||
imageAlt="Single Cell RNA Sequencing Workflow"
|
||||
useParagraphs={true}
|
||||
|
||||
@ -5,16 +5,15 @@ const SingleCellPipeline = ({
|
||||
svgContent = null, // Pass your SVG content here as JSX
|
||||
svgUrl = "/images/flowchart/singlecellrna.svg",
|
||||
backgroundColor = "bg-gray-50",
|
||||
textColor = "text-gray-700",
|
||||
className = "",
|
||||
titleClassName = "",
|
||||
svgClassName = "",
|
||||
containerClassName = ""
|
||||
}) => {
|
||||
return (
|
||||
<section className={`py-6 sm:py-8 lg:py-12 ${backgroundColor} ${className}`}>
|
||||
<section className={`py-6 sm:py-8 lg:py-4 ${backgroundColor} ${className}`}>
|
||||
<div className={`container mx-auto max-w-none px-3 sm:px-4 lg:px-6 ${containerClassName}`}>
|
||||
<h2 className={`${textColor} text-left pb-4 sm:pb-6 text-xl sm:text-2xl lg:text-3xl font-normal ${titleClassName}`}>
|
||||
<h2 className={"text-3xl font-bold text-teal-700 mb-4"}>
|
||||
{title}
|
||||
</h2>
|
||||
|
||||
@ -22,19 +21,19 @@ const SingleCellPipeline = ({
|
||||
<div className="bg-white rounded-xl shadow-lg p-4 sm:p-6 lg:p-8">
|
||||
<div className="flex justify-center">
|
||||
<div className="w-full max-w-6xl">
|
||||
{/* SVG Container with responsive sizing */}
|
||||
<div className={`w-full ${svgClassName}`}>
|
||||
{/* SVG Container with responsive sizing and reduced height */}
|
||||
<div className={`w-full max-h-100 overflow-hidden ${svgClassName}`}>
|
||||
{svgUrl ? (
|
||||
// If SVG URL/path is provided
|
||||
<img
|
||||
src={svgUrl}
|
||||
alt="Flowchart diagram"
|
||||
className="w-full h-auto object-contain"
|
||||
className="w-full h-auto object-contain max-h-100"
|
||||
/>
|
||||
) : svgContent ? (
|
||||
// If SVG content is provided as JSX
|
||||
<div className="w-full">
|
||||
<div className="w-full">
|
||||
<div className="w-full max-h-100">
|
||||
<div className="w-full max-h-100 overflow-hidden">
|
||||
{svgContent}
|
||||
</div>
|
||||
</div>
|
||||
|
||||
@ -5,16 +5,15 @@ const SRNABioinformatics = ({
|
||||
svgContent = null, // Pass your SVG content here as JSX
|
||||
svgUrl = "/images/flowchart/smallrna.svg",
|
||||
backgroundColor = "bg-gray-50",
|
||||
textColor = "text-gray-700",
|
||||
className = "",
|
||||
titleClassName = "",
|
||||
svgClassName = "",
|
||||
containerClassName = ""
|
||||
}) => {
|
||||
return (
|
||||
<section className={`py-6 sm:py-8 lg:py-12 ${backgroundColor} ${className}`}>
|
||||
<section className={`py-6 sm:py-8 lg:py-4 ${backgroundColor} ${className}`}>
|
||||
<div className={`container mx-auto max-w-none px-3 sm:px-4 lg:px-6 ${containerClassName}`}>
|
||||
<h2 className={`${textColor} text-left pb-4 sm:pb-6 text-xl sm:text-2xl lg:text-3xl font-normal ${titleClassName}`}>
|
||||
<h2 className={"text-3xl font-bold text-teal-700 mb-4"}>
|
||||
{title}
|
||||
</h2>
|
||||
|
||||
@ -22,19 +21,19 @@ const SRNABioinformatics = ({
|
||||
<div className="bg-white rounded-xl shadow-lg p-4 sm:p-6 lg:p-8">
|
||||
<div className="flex justify-center">
|
||||
<div className="w-full max-w-6xl">
|
||||
{/* SVG Container with responsive sizing */}
|
||||
<div className={`w-full ${svgClassName}`}>
|
||||
{/* SVG Container with responsive sizing and reduced height */}
|
||||
<div className={`w-full max-h-180 overflow-hidden ${svgClassName}`}>
|
||||
{svgUrl ? (
|
||||
// If SVG URL/path is provided
|
||||
<img
|
||||
src={svgUrl}
|
||||
alt="Flowchart diagram"
|
||||
className="w-full h-auto object-contain"
|
||||
className="w-full h-auto object-contain max-h-180"
|
||||
/>
|
||||
) : svgContent ? (
|
||||
// If SVG content is provided as JSX
|
||||
<div className="w-full">
|
||||
<div className="w-full">
|
||||
<div className="w-full max-h-180">
|
||||
<div className="w-full max-h-180 overflow-hidden">
|
||||
{svgContent}
|
||||
</div>
|
||||
</div>
|
||||
|
||||
@ -2,17 +2,25 @@
|
||||
import IntroductionLayout from '../../../components/shared/IntroductionLayout';
|
||||
|
||||
const SRNAIntroduction = () => {
|
||||
const contentItems = [
|
||||
const introItems = [
|
||||
"Small RNA sequencing (sRNA-seq) is designed to identify and analyze small non-coding RNAs (ncRNAs) that are under 200 nucleotides in length. These small RNAs, including microRNAs (miRNAs), small interfering RNAs (siRNAs), small nucleolar RNAs (snoRNAs), PIWI-interacting RNAs (piRNAs), and trans-acting siRNAs (tasiRNAs), play crucial roles in gene silencing and post-transcriptional regulation.",
|
||||
"The sRNA-seq workflow involves isolating miRNAs from samples, followed by preparing libraries with specific adapters and sequencing them using high-throughput platforms.",
|
||||
"The bioinformatics pipeline for sRNA-seq encompasses data preprocessing, alignment with reference genomes, and identification of small RNA species. This analysis includes differential expression studies, characterization of novel small RNAs, and pathway analysis to gain functional insights into sRNA-target interactions.",
|
||||
"Facilitates the discovery of novel small RNAs and offers detailed insights into their expression and functions. It links post-transcriptional regulation to phenotypic outcomes, aiding in the understanding of disease mechanisms and the identification of new biomarkers."
|
||||
];
|
||||
const advantageItems = [
|
||||
"Provides a comprehensive view of the small RNA landscape by capturing a broad range of small RNA species, including miRNAs, siRNAs, snoRNAs, piRNAs, and tasiRNAs.",
|
||||
"Facilitates comparative studies by allowing the comparison of small RNA expression profiles across different conditions or species, supporting investigations into developmental, environmental, and disease-related changes.",
|
||||
"Identifies previously unmapped small RNAs and isoforms, as well as novel biomarkers, expanding the scope of genetic research and potential clinical applications.",
|
||||
"Enhances understanding of how post-transcriptional regulation affects phenotypes and offers detailed functional insights into small RNA-target interactions and their roles in various cellular pathways, improving the understanding of gene regulation and function."
|
||||
];
|
||||
|
||||
return (
|
||||
<IntroductionLayout
|
||||
title="Introduction and Workflow"
|
||||
contentItems={contentItems}
|
||||
introTitle="Introduction and Workflow"
|
||||
advantageTitle="Advantage"
|
||||
introItems={introItems}
|
||||
advantageItems={advantageItems}
|
||||
imageUrl="/images/rna/small_RNA_sequencing.png"
|
||||
imageAlt="Small RNA Sequencing Workflow"
|
||||
useParagraphs={true}
|
||||
|
||||
@ -21,7 +21,6 @@ export default function SmallRNASequencingPage() {
|
||||
breadcrumbs={breadcrumbs}
|
||||
/>
|
||||
<SRNAIntroduction />
|
||||
<SRNAAdvantages />
|
||||
<SRNABioinformatics />
|
||||
<SRNAApplications />
|
||||
<SRNASpecifications />
|
||||
|
||||
@ -2,17 +2,27 @@
|
||||
import IntroductionLayout from '../../../components/shared/IntroductionLayout';
|
||||
|
||||
const WTSIntroduction = () => {
|
||||
const contentItems = [
|
||||
const introItems = [
|
||||
"Whole Transcriptome Sequencing (WTS) comprehensively captures and quantifies all RNA transcripts, both coding (mRNA) and long non-coding (rRNA, tRNA), providing an in-depth view of gene expression.",
|
||||
"This method combines a ribosomal RNA depletion strategy with Illumina NGS technology for efficient and precise results. The approach (1) reduces ribosomal contamination and increases the proportion of uniquely mapped reads, and (2) is particularly beneficial for species, such as bacteria, whose mRNA may lack a poly-A tail.",
|
||||
"The bioinformatics pipeline includes data preprocessing, genome mapping, transcript identification, and downstream analyses like differential expression analysis, lncRNA target gene analysis, GO enrichment analysis, and KEGG enrichment analysis.",
|
||||
"This technique is applicable to a wide range of species, including humans, mouse, rat, other animals, plants, and prokaryotes. It is compatible with various samples like; high and low-quality RNA samples, cell-free RNA, formalin-fixed paraffin-embedded (FFPE) tissues and RNA."
|
||||
];
|
||||
const advantageItems = [
|
||||
"Enables the identification of novel transcripts, alternative splicing events, post-transcriptional modifications, and gene fusions without prior knowledge, making it ideal for exploratory research.",
|
||||
"Analyzing the entire transcriptome helps gain a deeper understanding of gene regulation, cellular responses, and pathways, leading to a more comprehensive view of biological processes.",
|
||||
"Enables allele-specific gene expression analysis, offering valuable insights into gene regulation and genetic variability.",
|
||||
"Facilitates higher detection rates of gene fusions, indels, SNPs, and other genetic variations, offering greater reliability in research outcomes.",
|
||||
"Widely used in fields such as cancer research and developmental biology, WTS uncovers complex molecular mechanisms and aids in the discovery of potential biomarkers.",
|
||||
"Provides valuable insights into bacterial gene expression, helping to unravel the mysteries of gene regulation, host-pathogen interactions, antibiotic resistance, and the underlying causes of various diseases."
|
||||
];
|
||||
|
||||
return (
|
||||
<IntroductionLayout
|
||||
title="Introduction and Workflow"
|
||||
contentItems={contentItems}
|
||||
introTitle="Introduction and Workflow"
|
||||
advantageTitle="Advantage"
|
||||
introItems={introItems}
|
||||
advantageItems={advantageItems}
|
||||
imageUrl="/images/rna/total_rna_sequencing.png"
|
||||
imageAlt="Whole Transcriptome Sequencing Workflow"
|
||||
useParagraphs={true}
|
||||
|
||||
@ -5,16 +5,15 @@ const WTSPipeline = ({
|
||||
svgContent = null, // Pass your SVG content here as JSX
|
||||
svgUrl = "/images/flowchart/totalrna.svg",
|
||||
backgroundColor = "bg-gray-50",
|
||||
textColor = "text-gray-700",
|
||||
className = "",
|
||||
titleClassName = "",
|
||||
svgClassName = "",
|
||||
containerClassName = ""
|
||||
}) => {
|
||||
return (
|
||||
<section className={`py-6 sm:py-8 lg:py-12 ${backgroundColor} ${className}`}>
|
||||
<section className={`py-6 sm:py-8 lg:py-4 ${backgroundColor} ${className}`}>
|
||||
<div className={`container mx-auto max-w-none px-3 sm:px-4 lg:px-6 ${containerClassName}`}>
|
||||
<h2 className={`${textColor} text-left pb-4 sm:pb-6 text-xl sm:text-2xl lg:text-3xl font-normal ${titleClassName}`}>
|
||||
<h2 className={"text-3xl font-bold text-teal-700 mb-4"}>
|
||||
{title}
|
||||
</h2>
|
||||
|
||||
@ -22,19 +21,19 @@ const WTSPipeline = ({
|
||||
<div className="bg-white rounded-xl shadow-lg p-4 sm:p-6 lg:p-8">
|
||||
<div className="flex justify-center">
|
||||
<div className="w-full max-w-6xl">
|
||||
{/* SVG Container with responsive sizing */}
|
||||
<div className={`w-full ${svgClassName}`}>
|
||||
{/* SVG Container with responsive sizing and reduced height */}
|
||||
<div className={`w-full max-h-180 overflow-hidden ${svgClassName}`}>
|
||||
{svgUrl ? (
|
||||
// If SVG URL/path is provided
|
||||
<img
|
||||
src={svgUrl}
|
||||
alt="Flowchart diagram"
|
||||
className="w-full h-auto object-contain"
|
||||
className="w-full h-auto object-contain max-h-180"
|
||||
/>
|
||||
) : svgContent ? (
|
||||
// If SVG content is provided as JSX
|
||||
<div className="w-full">
|
||||
<div className="w-full">
|
||||
<div className="w-full max-h-180">
|
||||
<div className="w-full max-h-180 overflow-hidden">
|
||||
{svgContent}
|
||||
</div>
|
||||
</div>
|
||||
|
||||
@ -21,7 +21,6 @@ export default function WholeTranscriptomeSequencingPage() {
|
||||
breadcrumbs={breadcrumbs}
|
||||
/>
|
||||
<WTSIntroduction />
|
||||
<WTSAdvantages />
|
||||
<WTSPipeline/>
|
||||
<WTSApplications />
|
||||
<WTSSpecifications />
|
||||
|
||||
Reference in New Issue
Block a user