diff --git a/app/components/PackagingShipping/DNASamples.jsx b/app/components/PackagingShipping/DNASamples.jsx index 8c61468..9d1c536 100644 --- a/app/components/PackagingShipping/DNASamples.jsx +++ b/app/components/PackagingShipping/DNASamples.jsx @@ -5,7 +5,7 @@ const DNASamples = () => { return (
- Bioanalyzer QC report is advised to be shared from the client's end, in the - absence of which an agarose Gel Electrophoresis and Nanodrop quantification - to confirm the integrity of RNA must be shared. Samples with A260/280 ratio - values of ~1.8 are considered "pure" for DNA and will be accepted for - processing further. -
- -- We require Bioanalyzer traces (or similar) for all customer-submitted - sequencing libraries and total RNA samples. If traces are not provided, we - will perform Bioanalyzer QC for an additional fee. If you can supply traces, - please include them into the shipment in hard copy. Also, ensure that your - samples meet the specified sample or library requirements [LINK]. -
- -- For large-scale projects, RNA samples can be submitted in strip tubes with - individually attached RNase-free caps. Pack the strips into racks (e.g., - empty pipet tip boxes) and ensure they are secured to prevent movement - during transport. -
- -- RNA, cells, bacteria, and frozen tissue samples should be stored in liquid - nitrogen for rapid freezing and then transported with dry ice. For longer - shipments, RNA samples can also be successfully shipped dry at room - temperature after LiCl/ethanol precipitation and ethanol washes; make sure - to mark the pellet's position on the tubes. -
+
+
We humbly offer a wide range of services, including genomics, transcriptomics,
metagenomics, epigenomics, single-cell sequencing, genotyping, microarray,
bioinformatics, and more. To help us deliver the best results for you, we request you to
diff --git a/app/components/SampleGuideline/SearchSampleRequirements.jsx b/app/components/SampleGuideline/SearchSampleRequirements.jsx
index 3dbcee9..8e9cf87 100644
--- a/app/components/SampleGuideline/SearchSampleRequirements.jsx
+++ b/app/components/SampleGuideline/SearchSampleRequirements.jsx
@@ -67,7 +67,7 @@ const SearchSampleRequirements = () => {
return (
DNA sequencing is a method used to determine the precise order of nucleotides
(adenine, thymine, cytosine, and guanine) in a DNA molecule. This information is
critical for understanding genetic information, mutations, and their roles in disease,
evolution, and various biological processes.
- Different DNA sequencing approaches using Next Generation sequencing are listed below:
-
Different DNA sequencing approaches and their applications are summarized below:
+
Empowering you with precise, tailored approaches to diagnostics and care —
addressing the unique needs of each clinical area to improve patient outcomes.
- At Operify Health, we believe every patient deserves answers that are not only
- accurate — but actionable. By harnessing the power of Next Generation Sequencing
- (NGS), we transform patient samples into rich genomic insights that enable
- clinicians and oncologists to make informed, personalized decisions. From rare
- genetic disorders to complex oncological cases, our solutions help uncover what
- traditional diagnostics often miss.
-
- Our strength lies in our multidisciplinary team of researchers, bioinformaticians,
- and data scientists who use custom-built algorithms and cutting-edge analytics to
- interpret genetic data with unmatched depth. Backed by curated scientific evidence
- and real-world clinical findings, we deliver recommendations that are current,
- relevant, and patient-focused.
-
- With every genome we decode, we move closer to truly personalized medicine —
- bridging data and care, science and life.
-
+
Empowering you with precise, tailored approaches to diagnostics and care —
addressing the unique needs of each clinical area to improve patient outcomes.
- At Operify Health, we believe every patient deserves answers that are not only
- accurate — but actionable. By harnessing the power of Next Generation Sequencing
- (NGS), we transform patient samples into rich genomic insights that enable
- clinicians and oncologists to make informed, personalized decisions. From rare
- genetic disorders to complex oncological cases, our solutions help uncover what
- traditional diagnostics often miss.
-
- Our strength lies in our multidisciplinary team of researchers, bioinformaticians,
- and data scientists who use custom-built algorithms and cutting-edge analytics to
- interpret genetic data with unmatched depth. Backed by curated scientific evidence
- and real-world clinical findings, we deliver recommendations that are current,
- relevant, and patient-focused.
-
- With every genome we decode, we move closer to truly personalized medicine —
- bridging data and care, science and life.
-
- About 5-10% of all cancers are linked to inherited genetic mutations, often going
- undetected until late stages or after multiple family members are affected.
-
- The Operify Hereditary Cancer Panel screens key high- and moderate-risk genes associated
- with hereditary cancer syndromes like HBOC, Lynch Syndrome (LS), Li Fraumeni Syndrome (LFS),
- Familial Adenomatous Polyposis (FAP), Cowden Syndrome (CS), Peutz-Jeghers Syndrome (PJS),
- Neurofibromatosis (NF) etc.
-
- Early identification of germline mutations enables proactive clinical decisions, including
- risk-reducing strategies, targeted surveillance, and family cascade testing.
-
- Studies show that genetic testing in hereditary cancer cases improves outcomes and informs
- care for both patients and at-risk relatives.
-
+ {idx === 0 ? "About 5-10% of all cancers are linked to inherited genetic mutations" : ""}
+ {idx === 0 ? ", often going undetected until late stages or after multiple family members are affected." : point}
+
- Cancer is not a single disease—it's a highly complex and dynamic group of disorders,
- often driven by a multitude of genomic alterations. Despite advancements in treatment,
- many patients still face uncertainty due to incomplete or delayed molecular diagnoses.
-
- At Operify Health, we recognize that behind every tumor is a unique genetic story waiting
- to be told. Our precision oncology solutions utilize high-throughput Next Generation
- Sequencing (NGS) to analyze both somatic and germline mutations—providing clinicians
- with actionable insights that inform targeted therapies, immunotherapy decisions, and
- hereditary cancer risk assessments.
-
- This genomic-driven approach is especially critical in advanced and treatment-resistant
- cancers, where conventional methods often fall short. Studies have shown that integrating
- broad-panel NGS into cancer care can impact clinical decision-making in up to 30% of cases,
- leading to more personalized and effective treatment strategies.
-
- By combining cutting-edge sequencing, advanced bioinformatics, and curated clinical evidence,
- Operify Health empowers oncologists to move from uncertainty to precision—ensuring every cancer
- patient's care is as individualized as their diagnosis.
-
- About 5-10% of all cancers are linked to inherited genetic mutations, often going
- undetected until late stages or after multiple family members are affected.
-
- The Operify Hereditary Cancer Panel screens key high- and moderate-risk genes associated
- with hereditary cancer syndromes like HBOC, Lynch Syndrome (LS), Li Fraumeni Syndrome (LFS),
- Familial Adenomatous Polyposis (FAP), Cowden Syndrome (CS), Peutz-Jeghers Syndrome (PJS),
- Neurofibromatosis (NF) etc.
-
- Early identification of germline mutations enables proactive clinical decisions, including
- risk-reducing strategies, targeted surveillance, and family cascade testing.
-
- Studies show that genetic testing in hereditary cancer cases improves outcomes and informs
- care for both patients and at-risk relatives.
-
+ {idx === 0 ? "About 5-10% of all cancers are linked to inherited genetic mutations" : ""}
+ {idx === 0 ? ", often going undetected until late stages or after multiple family members are affected." : point}
+
- Cancer is not a single disease—it's a highly complex and dynamic group of disorders,
- often driven by a multitude of genomic alterations. Despite advancements in treatment,
- many patients still face uncertainty due to incomplete or delayed molecular diagnoses.
-
- At Operify Health, we recognize that behind every tumor is a unique genetic story waiting
- to be told. Our precision oncology solutions utilize high-throughput Next Generation
- Sequencing (NGS) to analyze both somatic and germline mutations—providing clinicians
- with actionable insights that inform targeted therapies, immunotherapy decisions, and
- hereditary cancer risk assessments.
-
- This genomic-driven approach is especially critical in advanced and treatment-resistant
- cancers, where conventional methods often fall short. Studies have shown that integrating
- broad-panel NGS into cancer care can impact clinical decision-making in up to 30% of cases,
- leading to more personalized and effective treatment strategies.
-
- By combining cutting-edge sequencing, advanced bioinformatics, and curated clinical evidence,
- Operify Health empowers oncologists to move from uncertainty to precision—ensuring every cancer
- patient's care is as individualized as their diagnosis.
-
- Whole Exome Sequencing (WES) targets the protein-coding regions of the genome, where most
- disease-causing mutations are found.
-
- With over 7,000 rare diseases identified—80% of which have a genetic basis—WES offers a
- powerful approach to uncover their causes.
-
- Traditional diagnostic methods can be slow, costly, and inconclusive; WES streamlines the
- process by delivering broad genetic insights in a single test.
-
- Operify Exome enhances WES by combining comprehensive coverage with advanced interpretation,
- improving diagnostic yield and patient outcomes.
-
+ {point}
+
- The Operify ExomeMito Panel offers a unified solution by integrating whole exome sequencing
- with complete mitochondrial genome analysis—addressing both nuclear and mitochondrial causes
- of disease.
-
- This combined approach is especially valuable in diagnosing complex, multisystemic, and rare
- disorders, where variants may exist across both genomes.
-
- Mitochondrial disorders, though individually rare, are clinically significant, affecting
- approximately 1 in 5,000 individuals and often missed in standard testing.
-
- Studies show that adding mitochondrial sequencing to exome testing increases diagnostic
- yield by up to 20%, offering greater clarity and clinical confidence. (PMID: 30369941)
-
- While screening for rare genetic disorders, it's essential not to overlook the rarest among
- them-mitochondrial disorders, which occur in approximately 1 in 5,000 individuals. Although
- individually rare, their cumulative impact is significant in the context of rare disease
- diagnostics. Multiple studies have demonstrated a substantial increase in diagnostic yield—up
- to 20%—when mitochondrial genome sequencing is performed alongside whole exome sequencing.
- Reference: PMID: 30369941
-
+ {point}
+
- There are over 7,000 identified rare diseases, many of which begin in childhood—and
- nearly 80% have a genetic cause. Yet, the average time to diagnose a rare disorder is
- still 4.8 years, with some cases taking up to 20 years.
-
- At Operify Health, we leverage advanced Next Generation Sequencing (NGS) and proprietary
- bioinformatics to deliver rapid, reliable insights—helping reduce the diagnostic journey
- from years to days.
- 21 Days Blood/Saliva/Cheek Swab/Genomic DNA/Dry Blood Spot
+ {req.description}
+
+ Comprehensive genomic sequencing solutions designed to unlock genetic insights
+ and accelerate diagnosis for rare disease patients and their families.
+ {sol.desc} {sol.desc}
- Whole Exome Sequencing (WES) is recommended for individuals with unexplained genetic
- disorders, complex or atypical clinical presentations, or when prior genetic tests
- have been inconclusive.
-
- It is especially valuable in diagnosing rare inherited diseases, uncovering the cause
- of developmental delays, intellectual disabilities, or early-onset neurological
- conditions, and providing insights for personalized treatment planning.
-
- WES can help identify genetic causes in a wide range of rare disorders.
-
+ {point}
+
RNA sequencing (RNA-Seq) is a method used to determine the sequence and quantity of RNA present in a sample, providing insight into gene expression, alternative splicing, and non-coding RNA functions. It is essential for understanding various biological processes, including disease mechanisms, gene regulation, and cellular responses.
- Different RNA sequencing approaches using Next-Generation Sequencing (NGS) are listed below:
- Search Sample Requirements
+ Search Sample Requirements
+
Welcome to Our Online Submission Portal!
{step.items.map((item, index) => (
-
diff --git a/app/components/SampleInitiation/SampleInitiationPage.jsx b/app/components/SampleInitiation/SampleInitiationPage.jsx
index 6887741..29bdbcc 100644
--- a/app/components/SampleInitiation/SampleInitiationPage.jsx
+++ b/app/components/SampleInitiation/SampleInitiationPage.jsx
@@ -1,14 +1,14 @@
import React from 'react';
import PageTitle from './PageTitle';
import ProcessSection from './ProcessSection';
-import ContactNote from './ContactNote';
+// import ContactNote from './ContactNote';
const SampleInitiationPage = () => {
return (
+
About DNA Sequencing
Exploring Life's Blueprint with Every Sequence
- DNA Sequencing Approaches
+ DNA Sequencing Approaches
+
@@ -146,7 +146,7 @@ const DNATable = () => {
{sequencingData.map((row, index) => (
{features.map((feature, idx) => (
-
-
+
{row.approach.name}
diff --git a/app/health/Components/ClinicalAreas.jsx b/app/health/Components/ClinicalAreas.jsx
index 0b9ee19..9a52c1a 100644
--- a/app/health/Components/ClinicalAreas.jsx
+++ b/app/health/Components/ClinicalAreas.jsx
@@ -6,12 +6,12 @@ export default function ClinicalAreas() {
return (
+
Precise Solutions for Clinical Areas
{/* Subtext */}
- About Health
-
- {/* Intro Section */}
-
+
+
+
Precise Solutions for Clinical Areas
{/* Subtext */}
- About Health
-
- {/* Intro Section */}
-
+
+ Operify Hereditary Cancer Panel
+ Operify Hereditary Cancer Panel
+ {points.map((point, idx) => (
+
Key Features
@@ -45,7 +48,7 @@ export default function HereditaryCancerPanel() {
+
diff --git a/app/health/oncology/Components/OncologyIntro.jsx b/app/health/oncology/Components/OncologyIntro.jsx
index 448bda3..7d1b1a3 100644
--- a/app/health/oncology/Components/OncologyIntro.jsx
+++ b/app/health/oncology/Components/OncologyIntro.jsx
@@ -1,31 +1,52 @@
export default function OncologyIntro() {
return (
- {feature.title}
{feature.desc}
Oncology
- Turning Complexity into Clarity
-
+ Turning Complexity into Clarity
+
+
+
+ Operify Hereditary Cancer Panel
+ Operify Hereditary Cancer Panel
+ {points.map((point, idx) => (
+
Key Features
@@ -45,7 +48,7 @@ export default function HereditaryCancerPanel() {
{features.map((feature, idx) => (
-
+
diff --git a/app/health/oncology/components/OncologyIntro.jsx b/app/health/oncology/components/OncologyIntro.jsx
index 448bda3..7d1b1a3 100644
--- a/app/health/oncology/components/OncologyIntro.jsx
+++ b/app/health/oncology/components/OncologyIntro.jsx
@@ -1,31 +1,52 @@
export default function OncologyIntro() {
return (
- {feature.title}
{feature.desc}
Oncology
- Turning Complexity into Clarity
-
+ Turning Complexity into Clarity
+
+
+
+ Clinical Areas
+ Clinical Areas
Operify Exome
+ Operify Exome
+ {points.map((point, idx) => (
+
Key Features
+ Key Features
diff --git a/app/health/rare-disorders/components/OperifyExomeMito.jsx b/app/health/rare-disorders/components/OperifyExomeMito.jsx
index 08f42a7..c941f53 100644
--- a/app/health/rare-disorders/components/OperifyExomeMito.jsx
+++ b/app/health/rare-disorders/components/OperifyExomeMito.jsx
@@ -14,52 +14,48 @@ export default function OperifyExomeMito() {
{ genome: "Mitochondrial genome", coverage: "37 genes" }
];
+ const points = [
+ "The Operify ExomeMito Panel offers a unified solution by integrating whole exome sequencing with complete mitochondrial genome analysis—addressing both nuclear and mitochondrial causes of disease.",
+ "This combined approach is especially valuable in diagnosing complex, multisystemic, and rare disorders, where variants may exist across both genomes.",
+ "Mitochondrial disorders, though individually rare, are clinically significant, affecting approximately 1 in 5,000 individuals and often missed in standard testing.",
+ "Studies show that adding mitochondrial sequencing to exome testing increases diagnostic yield by up to 20%, offering greater clarity and clinical confidence. (PMID: 30369941)",
+ "While screening for rare genetic disorders, it's essential not to overlook the rarest among them-mitochondrial disorders, which occur in approximately 1 in 5,000 individuals. Although individually rare, their cumulative impact is significant in the context of rare disease diagnostics. Multiple studies have demonstrated a substantial increase in diagnostic yield—up to 20%—when mitochondrial genome sequencing is performed alongside whole exome sequencing. Reference: PMID: 30369941"
+ ];
+
return (
-
Operify ExomeMito
+ Operify ExomeMito
Boost diagnostic yield with Exome + Mito Sequencing
-
+ {points.map((point, idx) => (
+
Genome Coverage
+ Genome Coverage
-
- Genome
- Coverage
+
+
{genomeCoverage.map((item, idx) => (
- Genome
+ Coverage
+
@@ -69,18 +65,18 @@ export default function OperifyExomeMito() {
- {item.genome}
{item.coverage}
Key Features
+ Key Features
-
- Feature
- Description
+
+
{features.map((feature, idx) => (
- Feature
+ Description
+
diff --git a/app/health/rare-disorders/components/RareIntro.jsx b/app/health/rare-disorders/components/RareIntro.jsx
index 2e2cf9f..efcaeda 100644
--- a/app/health/rare-disorders/components/RareIntro.jsx
+++ b/app/health/rare-disorders/components/RareIntro.jsx
@@ -1,18 +1,33 @@
export default function RareIntro() {
return (
- {feature.title}
{feature.desc}
Rare Disorders
- Transforming Delays into Diagnoses
-
+ Transforming Delays into Diagnoses
+
+
+
+ {title} Sample Requirements
-
- Turnaround Time
- Sample Requirement
- {title} Sample Requirements
+
+ {req.title}
+ Our Rare Disease Solutions Offer
- Our Rare Disease Solutions Offer
+
+ {sol.name}
- {sol.name}
+
+
Who Should Consider Whole Exome Sequencing (WES)?
-
+ {points.map((point, idx) => (
+
+
About RNA Sequencing
@@ -16,9 +16,6 @@ const AboutRNA = () => {
RNA Sequencing Approaches
@@ -130,7 +130,7 @@ const RNATable = () => {
{sequencingData.map((row, index) => (
-
+
{row.approach.name}
diff --git a/public/images/icons/clock.png b/public/images/icons/clock.png
new file mode 100644
index 0000000..6829e39
Binary files /dev/null and b/public/images/icons/clock.png differ
diff --git a/public/images/icons/sample.png b/public/images/icons/sample.png
new file mode 100644
index 0000000..5a77858
Binary files /dev/null and b/public/images/icons/sample.png differ