37 lines
2.2 KiB
JavaScript
37 lines
2.2 KiB
JavaScript
// WGBSIntroduction.jsx
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import IntroductionLayout from '../../../../components/shared/IntroductionLayout';
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const WGBSIntroduction = () => {
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const contentItems = [
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"Whole Genome Bisulphite Sequencing (WGBS) maps DNA methylation patterns across an entire genome at single-base resolution, offering insights into transcriptional activity and gene regulation.",
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"The workflow includes DNA isolation, followed by treatment with sodium bisulfite (Gold standard method). This treatment converts unmethylated cytosines into uracils, which are subsequently amplified by PCR and sequenced.",
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"In bioinformatics analysis, sequencing data is aligned to a reference genome using advanced bioinformatics tools to determine the methylation status at CpG, CHG, and CHH sites.",
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"Valuable in epigenetic research for its ability to provide high-resolution insights into the regulatory mechanisms of the genome, offering a deeper understanding of cellular functions and molecular pathways."
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];
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const advantageItems = [
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"Provides high-resolution mapping of DNA methylation patterns across the genome, including CpG, CHG, and CHH sites, offering detailed insights into epigenetic modifications.",
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"Enables precise quantification of methylation levels, distinguishing between methylated and unmethylated cytosines based on read counts.",
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"This technique can detect effective CpG sites reaching over 75% of all CpG sites in the entire genome.",
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"Provides valuable insights into cell fate determination, genetic reprogramming, gene regulation, developmental epigenetics, disease mechanisms, and the identification of new epigenetic markers and therapeutic targets."
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];
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return (
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<IntroductionLayout
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introTitle="Introduction and Workflow"
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advantageTitle="Advantage"
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introItems={contentItems}
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advantageItems={advantageItems}
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imageUrl="/images/dna/whole_genome_bisulphate_sequencing.png"
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imageAlt="WGBS Workflow"
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badgeText="WGBS WORKFLOW"
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badgeSubtext="Workflow from Whole Genome Bisulfite Sequencing (WGBS)"
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backgroundColor="#f8f9fa"
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badgeColor="bg-teal-600"
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useParagraphs={true}
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/>
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);
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};
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export default WGBSIntroduction; |